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Bianca Hopes "The B" Group

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Frank Pruett
Frank Pruett

Where Can I Buy Magic Mouthwash

People going through cancer treatment can experience some uncomfortable side effects, including mucositis caused by chemotherapy and radiation treatment. Magic mouthwash is only one of several treatments that may help alleviate the pain from mouth sores, dry mouth, and inflammation caused by mucositis. Learn more about magic mouthwash and how it may benefit those dealing with mucositis.

where can i buy magic mouthwash

Chemotherapy and radiation treatments kill cancer cells, but the treatments can lead to uncomfortable or painful side effects in the mouth and throat, such as oral mucositis. "Magic mouthwash" is the term for an analgesic mouthrinse designed to help relieve the pain of mucositis symptoms. Oral mucositis symptoms include dry mouth, swollen and inflamed gums, difficulty swallowing, and mouth sores.

Magic mouthwash is a commonly prescribed treatment for mouth sores caused by mucositis, and it may help ease the pain in your mouth and reduce your risk of infection. Talk with your healthcare team to see if magic mouthwash is right for you.

Magic mouthwash is a prescription-only topical treatment with the power to ward off mouth sores. But is it a bona fide treatment or sleight of hand? Internal medicine doctor Janet Morgan, MD, unlocks the secrets behind the magic.

A small 2015 study found that morphine mouthwash may be better than magic mouthwash at treating mouth sores. The study subjects included 30 adults who were being treated for head and neck cancer. More research is needed to confirm the results.

The researchers concluded that magic mouthwash was just as effective as the 0.15 percent benzydamine hydrochloride in helping prevent the development of mouth sores in people undergoing radiotherapy for head and neck cancer.

So-called magic mouthwash, a treatment for oral inflammation and pain caused by cancer therapies, is ineffective, and clinicians would be well served by its "vanishing into thin air," concludes an essay published online November 19 in JAMA Internal Medicine.

A lone randomized, double-blind trial conducted in 2000 compared the efficacy of three different oral rinses: chlorhexidine; salt and baking soda; and magic mouthwashes, including one containing lidocaine, diphenhydramine, and aluminum hydroxide. There were no differences among the rinses with respect to ratings of pain relief or time to cessation of symptoms.

A 2013 systematic review concluded that for oral mucositis, which is the catchall term for tissue damage caused by systemic chemotherapy and by radiotherapy to the head and neck, no evidence supported the use of the mouthwashes.

"Careful dental care with a soft toothbrush and rinses with an inexpensive, homemade salt and sodium bicarbonate mouthwash (1 teaspoon of salt and sodium bicarbonate each in 1 liter of water) are advised," they write.

Magic mouthwash is an umbrella term for a compounded mouthwash that doctors use to treat mouth sores. The term miracle mouthwash is one we commonly use as well. Most often someone will use them during chemo treatment if they develop mouth sores or if they have a medical condition or disease that causes severe mouth sores. If sores are from an ill fitting denture please fix the denture.

There are many formulations for miracle mouthwash, and different doctors will use slightly different formulations. The most common recipe is equal parts of Benadryl, Maalox, and lidocaine. The Benadryl is to reduce itching that is likely from the inflammation. The Maalox simply increases the thickness and the ability of the solution to stay in the mouth. Finally, the lidocaine is to numb the pain.

We have found some of our patients actually prefer Rincinol over the magic/miracle mouthwash. Rincinol is basically aloe vera extract mouth rinse which comes in small liquid packages or bottles. We have patients use it 2-10 times a day, they will take half the package and swish for 1 minute and spit it out. It is not harmful if someone swallows some on accident, however the idea is to not swallow any.

Pharmacologic agents such as topical analgesics, high-potency corticosteroids (dexamethasone mouthwash), anesthetics, and nonsteroidal anti-inflammatories can be incorporated into existing treatments to manage side effects.

Recommended daily use: Shake vigorously. Dispense approximately 1 tsp in your mouth (1 capful), swish for two to five minutes, then spit out. No need to rinse afterwards. For a milder mouthwash, follow first time user directions below.

Two medicated mouthwashes led to reductions in oral mucositis pain for head and neck cancer patients treated with radiotherapy, but not at a level deemed clinically important, a randomized phase III study found.

Within 4 hours of radiotherapy, pain from oral mucositis dropped by 11.7 points (as defined by the area under the curve) with a diphenhydramine-lidocaine-antacid rinse -- or "magic mouthwash" -- and 11.6 points with a doxepin mouthwash, compared with 8.7 points with placebo, reported Robert C. Miller, MD, MS, MBA, of the University of Maryland School of Medicine in Baltimore, and colleagues.

Over 80% of radiotherapy- and chemoradiotherapy-treated head and neck cancer patients develop the painful and debilitating complication, with severe symptoms requiring hospitalization and feeding tubes, they explained. Systemic analgesics and mouthwashes are frequently used to manage the condition.

"These data tell us that magic mouthwash (or doxepin) is not the sole answer to managing mucositis -- physicians should not prescribe magic mouthwash and expect magic!" Arjun Gupta, MD, of the Sidney Kimmel Comprehensive Cancer Center in Baltimore, told MedPage Today in an email. "We have very few drugs to treat [these] patients in great suffering, and we need more drugs in well-designed trials to urgently address this question."

Gupta, who was not involved in the research, previously co-authored a perspective calling into question the routine use of magic mouthwash for oral mucositis, with issues ranging from the limited efficacy, potential for high out-of-pocket costs, among other concerns.

"In the real world, there is no fixed formula for magic mouthwash. Most providers do not know the contents or concentrations of the ingredients in these mixed-medication formulations," he said. "They could also contain unnecessary and harmful ingredients such as steroids and antibacterials/antifungals. How many other drugs do physicians prescribe without knowing the contents or concentration?"

"Given the ease of preparation at home and almost no cost (1 teaspoon of salt and sodium bicarbonate each in 1 liter of water), salt and soda mouthwash is often prescribed by physicians," he said, adding that had this been used in place of the placebo, or as a fourth study arm, it might have demonstrated equivalence or superiority over the investigational agents.

Grade 3 adverse events occurred in three patients in each of the investigational arms (4%) versus two patients in the placebo group (2%), and five patients receiving the doxepin mouthwash reported fatigue (6%) versus none in the other two arms.

For the Alliance A221304 study, Miller's team randomized 275 patients (1:1:1) at 30 institutions in the U.S. from 2014 to 2016. All patients had a minimum pain score of 4 (out of 10). In all, 92 patients received the 25-mg doxepin mouthwash (in a 5-mL solution), 92 received a 5-mL placebo mouthwash consisting of water and Ora-Sweet SF (2.5 mL each), and 91 received a 5-mL solution of 12.5 mg diphenhydramine, 2% lidocaine, and an antacid (200 mg of aluminum hydroxide, 200 mg of magnesium hydroxide, and 20 mg of simethicone).

Magic mouthwash is used to treat oral mucositis associated with chemotherapy or radiation. The composition of magic mouthwash varies widely and may include antibiotics, antihistamines, local anesthetics, antifungals, corticosteroids, or antacids. The majority of magic mouthwash formulations are intended to be held in the mouth for one to two minutes and then spit or swallowed.

2. Important - Before dispensing, tap the top and bottom of the bottle containing diphenhydramine hydrochloride to loosen the powder and remove the cap. Empty the diphenhydramine hydrochloride powder into the bottle containing the mouthwash liquid suspension. Likewise, tap the top and bottom of the bottle containing lidocaine hydrochloride to loosen the powder and remove the cap. Empty the lidocaine hydrochloride powder into the bottle containing the mouthwash liquid suspension.

Method of Preparation: Calculate the quantity of each ingredient for the amount to be prepared. Accurately weigh or measure each ingredient. Before compounding, tap the top and bottom of the lidocaine hydrochloride (HCl) bottle. Open the suspension bottle and empty the lidocaine HCl powder into the suspension. Likewise, tap the top and bottom of the diphenhydramine HCl bottle. Remove the cap. Because of the hygroscopic nature and small volume of the powder, use the enclosed spatula to empty the contents into the mouthwash suspension. Close the suspension bottle and vigorously shake it vertically for approximately 20 to 30 seconds. The appropriate quantities of diphenhydramine HCl powder and lidocaine HCl powder have been packaged in each bottle to deliver the required dose of each drug. Residual quantities remaining in the bottles after emptying need not be rinsed out. Package and label.

Discussion: This formula is equivalent to the active ingredients in compounded Magic Mouthwash [Benadryl Elixir:Lidocaine HCl 2% Viscous:Maalox Suspension (1:1:1 v/v/v)]. The Mouthwash BLM Compounding Kit contains premeasured diphenhydramine HCl powder, lidocaine HCl powder, and mouthwash suspension (aluminum hydroxide, magnesium hydroxide, and simethicone, plus inactive ingredients). The 119-mL size of the compounded preparation contains diphenhydramine HCl 0.1 g, lidocaine HCl 0.8 g, and FIRST Mouthwash Suspension 118 mL.

Magic mouthwash is a type of oral rinse. It can relieve the symptoms of mouth sores and soft tissue trauma, such as burns. Doctors commonly prescribe it to help with oral mucositis, a painful side effect of head and neck cancer treatments.1 041b061a72


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